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Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition.
Glas, Carina; Naydenova, Eli; Lechner, Severin; Wössner, Nathalie; Yang, Liu; Dietschreit, Johannes C B; Sun, Hongyan; Jung, Manfred; Kuster, Bernhard; Ochsenfeld, Christian; Bracher, Franz.
Afiliação
  • Glas C; Department of Pharmacy, Center for Drug Research, Ludwig-Maximilians University, Butenandtstraße 5-13, 81377, Munich, Germany.
  • Naydenova E; Theoretical Chemistry, Department of Chemistry, Ludwig-Maximilians University, Butenandtstraße 7, 81377, Munich, Germany.
  • Lechner S; Proteomics and Bioanalytics, Technical University of Munich, Emil-Erlenmeyer-Forum 5, 85354, Freising, Germany.
  • Wössner N; Institute of Pharmaceutical Sciences, Albert-Ludwigs-University Freiburg, Albertstraße 25, 79104, Freiburg im Breisgau, Germany.
  • Yang L; Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China.
  • Dietschreit JCB; Theoretical Chemistry, Department of Chemistry, Ludwig-Maximilians University, Butenandtstraße 7, 81377, Munich, Germany.
  • Sun H; Department of Chemistry and COSDAF (Centre of Super-Diamond and Advanced Films), City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China.
  • Jung M; Institute of Pharmaceutical Sciences, Albert-Ludwigs-University Freiburg, Albertstraße 25, 79104, Freiburg im Breisgau, Germany.
  • Kuster B; Proteomics and Bioanalytics, Technical University of Munich, Emil-Erlenmeyer-Forum 5, 85354, Freising, Germany; Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich, Emil-Erlenmeyer-Forum 5, 85354, Freising, Germany.
  • Ochsenfeld C; Theoretical Chemistry, Department of Chemistry, Ludwig-Maximilians University, Butenandtstraße 7, 81377, Munich, Germany.
  • Bracher F; Department of Pharmacy, Center for Drug Research, Ludwig-Maximilians University, Butenandtstraße 5-13, 81377, Munich, Germany. Electronic address: franz.bracher@cup.uni-muenchen.de.
Eur J Med Chem ; 240: 114594, 2022 Oct 05.
Article em En | MEDLINE | ID: mdl-35853430
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sirtuínas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sirtuínas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article