Design, synthesis and insecticidal activities of 4-propargyloxybenzene sulfonamide derivatives substituted with amino acids.
J Asian Nat Prod Res
; 25(4): 379-386, 2023 Apr.
Article
em En
| MEDLINE
| ID: mdl-35866233
ABSTRACT
Sixty-nine 4-propargyloxybenzene sulfonamide derivatives with different amino acids as amino substituent were synthesized and evaluated for their insecticidal activity against third-instar Mythimna separate. The bioassay results revealed that some derivatives bearing amino acid ester group performed good insecticidal activity against third-instar M.separata, such as the LC50 values of D18 and D19 were 4.28 and 2.96 mg/ml after 48 h, in particular, the LC50 of D16 was 2.38 mg/ml and the activity was improved by 14 times compared to celangulin V (34.48 mg/ml). The above results provided theoretical and experimental basis for the discovery of novel insecticidal active compounds.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Inseticidas
/
Mariposas
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article