Preclinical evaluation of [<sup>18</sup>F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection.

Victorio, Carla Bianca Luena; Ong, Joanne; Tham, Jing Yang; Reolo, Marie Jennifer; Novera, Wisna; Msallam, Rasha; Watanabe, Satoru; Kalimuddin, Shirin; Low, Jenny G; Vasudevan, Subhash G; Chacko, Ann-Marie

Preclinical evaluation of [¹⁸F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection.

Victorio, Carla Bianca Luena; Ong, Joanne; Tham, Jing Yang; Reolo, Marie Jennifer; Novera, Wisna; Msallam, Rasha; Watanabe, Satoru; Kalimuddin, Shirin; Low, Jenny G; Vasudevan, Subhash G; Chacko, Ann-Marie.

Afiliação

Victorio CBL; Laboratory for Translational and Molecular Imaging, Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Ong J; Laboratory for Translational and Molecular Imaging, Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Tham JY; Laboratory for Translational and Molecular Imaging, Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Reolo MJ; Laboratory for Translational and Molecular Imaging, Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Novera W; Laboratory for Translational and Molecular Imaging, Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Msallam R; Laboratory for Translational and Molecular Imaging, Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Watanabe S; Programme in Emerging Infectious Disease, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Kalimuddin S; Programme in Emerging Infectious Disease, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Low JG; Department of Infectious Diseases, Singapore General Hospital, 20 College Road, Singapore, 169856, Singapore.
Vasudevan SG; Programme in Emerging Infectious Disease, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Chacko AM; Department of Infectious Diseases, Singapore General Hospital, 20 College Road, Singapore, 169856, Singapore.

Eur J Nucl Med Mol Imaging ; 49(13): 4516-4528, 2022 Nov.

Article em En | MEDLINE | ID: mdl-35876869

Assuntos

Infecção por Zika virus; Zika virus; Animais; Camundongos; Infecção por Zika virus/diagnóstico por imagem; Infecção por Zika virus/metabolismo; Infecção por Zika virus/patologia; Zika virus/metabolismo; Fluordesoxiglucose F18/metabolismo; Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada/métodos; Distribuição Tecidual; Tomografia Computadorizada por Raios X; Tomografia por Emissão de Pósitrons; Tecido Linfoide/metabolismo; Tecido Linfoide/patologia; Inflamação/diagnóstico por imagem; Inflamação/metabolismo; Modelos Animais de Doenças; Biomarcadores/metabolismo; Citocinas

Palavras-chave

AG129 mouse; Dengue; Viral infection; Viral inflammation; Zika; [18F]FDG

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Zika virus / Infecção por Zika virus Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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