An Elevated METS-IR Index Is Associated With Higher Asthma Morbidity and Earlier Age of First Asthma in US Adults: Results Based on a Cross-Sectional Study.
Front Endocrinol (Lausanne)
; 13: 920322, 2022.
Article
em En
| MEDLINE
| ID: mdl-35898458
ABSTRACT
Objective:
The purpose of this study was to evaluate whether there is a correlation between the METS-IR index and asthma among Americans.Methods:
In an attempt to establish the relationship between the METS-IR index and asthma prevalence and age at first onset of asthma, we conducted a logistic regression analysis, subgroup analysis, and dose-response curve analysis using the National Health and Nutrition Examination Survey (NHANES) database.Results:
In model 3, each unit increase in METS-IR index led to 1.5% increase in asthma prevalence (OR= 1.015, 95% CI 1.012, 1.018) and an earlier age of onset of asthma by 0.057years (ß= -0.057, 95% CI -0.112, -0.002).Stratified analysis determined that an increase in METS-IR index was associated with asthma prevalence in almost all subgroups, except in the group where it was not known whether a blood relative had asthma, and a positive linear relationship was found between METS-IR index and asthma prevalence, as well as a linear negative relationship with age at asthma onset.Conclusion:
Despite the fact that a direct causal relationship cannot be demonstrated, a higher METS-IR index is positively related to asthma prevalence and correspondingly may result in asthma onset at younger ages.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Resistência à Insulina
/
Síndrome Metabólica
Tipo de estudo:
Observational_studies
/
Prevalence_studies
Limite:
Adult
/
Humans
/
Newborn
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article