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Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies.
Kutkat, Omnia; Moatasim, Yassmin; Al-Karmalawy, Ahmed A; Abulkhair, Hamada S; Gomaa, Mokhtar R; El-Taweel, Ahmed N; Abo Shama, Noura M; GabAllah, Mohamed; Mahmoud, Dina B; Kayali, Ghazi; Ali, Mohamed A; Kandeil, Ahmed; Mostafa, Ahmed.
Afiliação
  • Kutkat O; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt.
  • Moatasim Y; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt.
  • Al-Karmalawy AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, 34518, Egypt.
  • Abulkhair HS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, 34518, Egypt.
  • Gomaa MR; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.
  • El-Taweel AN; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt.
  • Abo Shama NM; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt.
  • GabAllah M; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt.
  • Mahmoud DB; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt.
  • Kayali G; Pharmaceutics Department, Egyptian Drug Authority, formerly known as National Organization for Drug Control and Research, Giza, 12654, Egypt.
  • Ali MA; Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas, Houston, TX, 77030, USA.
  • Kandeil A; Human Link DMCC, Dubai, UAE.
  • Mostafa A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Dokki, Giza, 12622, Egypt.
Sci Rep ; 12(1): 12920, 2022 07 28.
Article em En | MEDLINE | ID: mdl-35902647
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Coronavírus da Síndrome Respiratória do Oriente Médio / Tratamento Farmacológico da COVID-19 Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Coronavírus da Síndrome Respiratória do Oriente Médio / Tratamento Farmacológico da COVID-19 Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article