ABC, ATP-Binding Cassette; APC, Antigen Presenting Cells; Alternate antifungal therapies; Antifungal resistance; BAD1, Blastomyces Adhesin-1; BBB, Blood Brain Barrier; Biofilm; CDC, Centers for Disease Control and Prevention; CNS, Central Nervous System; DC, Dendritic Cells; ERG, ETS-Related Gene; ETS, Erythoblast Transformation Specific; FCY, Fluorocytosine Deaminase; FDA, Food and Drug Administration; Fungal pathogenesis; G-CSF, Granulocyte-Colony Stimulating Factor; GM-CSF, Granulocyte-Macrophage Colony Stimulating Factor; HAI, Healthcare Associated Infections; HIV, Human Immunodeficiency Virus; Host-immune response; Hsp, Heat Shock Protein; IFN, Interferon; M-CSF, Macrophage-Colony Stimulating Factor; MFS, Major Facilitator Superfamily; NK, Natural Killer; PAMP, Pathogen Associated Molecular Pattern; PRR, Pattern Recognition Receptors; RNS, Reactive Nitrogen Species; ROS, Reactive Oxygen Species; TLR, Toll-Like Receptors