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Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state.
Siebert, Verena; Silber, Mara; Heuten, Elena; Muhle-Goll, Claudia; Lemberg, Marius K.
Afiliação
  • Siebert V; Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg, Germany; Center for Biochemistry and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Medical Faculty, University of Cologne, Cologne, Germany.
  • Silber M; Institute for Biological Interfaces 4, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
  • Heuten E; Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg, Germany; Center for Biochemistry and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Medical Faculty, University of Cologne, Cologne, Germany.
  • Muhle-Goll C; Institute for Biological Interfaces 4, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
  • Lemberg MK; Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg, Germany; Center for Biochemistry and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Medical Faculty, University of Cologne, Cologne, Germany. Electronic address: m.lemberg@uni-koe
J Biol Chem ; 298(9): 102321, 2022 09.
Article em En | MEDLINE | ID: mdl-35921890

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas Fosfatases / Proteínas Mitocondriais / Metaloproteases / Proteólise / Homeostase / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas Fosfatases / Proteínas Mitocondriais / Metaloproteases / Proteólise / Homeostase / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article