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A non-canonical vitamin K cycle is a potent ferroptosis suppressor.
Mishima, Eikan; Ito, Junya; Wu, Zijun; Nakamura, Toshitaka; Wahida, Adam; Doll, Sebastian; Tonnus, Wulf; Nepachalovich, Palina; Eggenhofer, Elke; Aldrovandi, Maceler; Henkelmann, Bernhard; Yamada, Ken-Ichi; Wanninger, Jonas; Zilka, Omkar; Sato, Emiko; Feederle, Regina; Hass, Daniela; Maida, Adriano; Mourão, André Santos Dias; Linkermann, Andreas; Geissler, Edward K; Nakagawa, Kiyotaka; Abe, Takaaki; Fedorova, Maria; Proneth, Bettina; Pratt, Derek A; Conrad, Marcus.
Afiliação
  • Mishima E; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany. eikan@med.tohoku.ac.jp.
  • Ito J; Division of Nephrology, Rheumatology and Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan. eikan@med.tohoku.ac.jp.
  • Wu Z; Laboratory of Food Function Analysis, Tohoku University, Sendai, Japan.
  • Nakamura T; Department of Chemistry and Biomolecular Science, University of Ottawa, Ottawa, Ontario, Canada.
  • Wahida A; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Doll S; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Tonnus W; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Nepachalovich P; Universitätsklinikum Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany.
  • Eggenhofer E; Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Leipzig, Germany.
  • Aldrovandi M; Zentrum Membranbiochemie und Lipidforschung, Medizinische Fakultät Carl Gustav Carus, Technical University, Dresden, Germany.
  • Henkelmann B; Department of Surgery, University Hospital Regensburg, University of Regensburg, Regensburg, Germany.
  • Yamada KI; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Wanninger J; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Zilka O; Physical Chemistry for Life Science Laboratory, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
  • Sato E; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Feederle R; Department of Chemistry and Biomolecular Science, University of Ottawa, Ottawa, Ontario, Canada.
  • Hass D; Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Sendai, Japan.
  • Maida A; Monoclonal Antibody Core Facility, Helmholtz Zentrum München, Neuherberg, Germany.
  • Mourão ASD; Institute for Diabetes and Cancer, Helmholtz Zentrum München, Neuherberg, Germany.
  • Linkermann A; Institute for Diabetes and Cancer, Helmholtz Zentrum München, Neuherberg, Germany.
  • Geissler EK; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Nakagawa K; Universitätsklinikum Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany.
  • Abe T; Department of Surgery, University Hospital Regensburg, University of Regensburg, Regensburg, Germany.
  • Fedorova M; Laboratory of Food Function Analysis, Tohoku University, Sendai, Japan.
  • Proneth B; Division of Nephrology, Rheumatology and Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan.
  • Pratt DA; Division of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan.
  • Conrad M; Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Leipzig, Germany.
Nature ; 608(7924): 778-783, 2022 08.
Article em En | MEDLINE | ID: mdl-35922516
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vitamina K / Ferroptose Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vitamina K / Ferroptose Idioma: En Ano de publicação: 2022 Tipo de documento: Article