Foxp2 inhibits Th9 cell differentiation and attenuates allergic airway inflammation in a mouse model of ovalbumin-induced asthma.

Zhang, Xinxing; Ma, Yu; He, Yanyu; Gu, Wenjing; Yan, Yongdong; Ji, Wei; Huang, Li; Wang, Yuqing; Hao, Chuangli; Li, Gang; Chen, Zhengrong

Zhang, Xinxing; Ma, Yu; He, Yanyu; Gu, Wenjing; Yan, Yongdong; Ji, Wei; Huang, Li; Wang, Yuqing; Hao, Chuangli; Li, Gang; Chen, Zhengrong.

Afiliação

Zhang X; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
Ma Y; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
He Y; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
Gu W; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
Yan Y; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
Ji W; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
Huang L; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
Wang Y; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China.
Hao C; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China. Electronic address: hcl_md@163.com.
Li G; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou 215025, China. Electronic address: ligangmailbox@hotmail.com.
Chen Z; Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou 215003, China. Electronic address: chen_zheng_rong@163.com.

Int Immunopharmacol ; 111: 109060, 2022 Oct.

Article em En | MEDLINE | ID: mdl-35930910

Assuntos

Asma; Animais; Asma/induzido quimicamente; Asma/tratamento farmacológico; Asma/metabolismo; Líquido da Lavagem Broncoalveolar; Diferenciação Celular; Modelos Animais de Doenças; Fatores de Transcrição Forkhead/genética; Inflamação; Pulmão/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Ovalbumina; Proteínas Repressoras; Linfócitos T Auxiliares-Indutores

Palavras-chave

Airway inflammation; Asthma; Foxp2; Th9 cell differentiation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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