Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems.

Subramanian, Deepak A; Langer, Robert; Traverso, Giovanni

Subramanian, Deepak A; Langer, Robert; Traverso, Giovanni.

Afiliação

Subramanian DA; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Langer R; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Traverso G; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

J Nanobiotechnology ; 20(1): 362, 2022 Aug 06.

Article em En | MEDLINE | ID: mdl-35933341

Assuntos

Sistemas de Liberação de Fármacos por Nanopartículas; Nanopartículas; Administração Oral; Expectorantes/metabolismo; Expectorantes/farmacologia; Trato Gastrointestinal/metabolismo; Humanos; Absorção Intestinal; Muco

Palavras-chave

Gastrointestinal tract; Mucoadhesive; Mucus; Mucus penetration; Oral delivery

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas / Sistemas de Liberação de Fármacos por Nanopartículas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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