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Developability Assessments of Monoclonal Antibody Candidates to Minimize Aggregation During Large-Scale Ultrafiltration and Diafiltration (UF-DF) Processing.
Whitaker, Neal; Pace, Samantha E; Merritt, Kimberly; Tadros, Madeleine; Khossravi, Mehrnaz; Deshmukh, Smeet; Cheng, Yuan; Joshi, Sangeeta B; Volkin, David B; Dhar, Prajnaparamita.
Afiliação
  • Whitaker N; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA.
  • Pace SE; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA; Department of Discovery Pharmaceutics, Bristol-Myers Squibb, Inc., 3551 Lawrenceville Road, Lawrence Township, NJ, 08648, USA.
  • Merritt K; Bioengineering Program, School of Engineering, The University of Kansas, 1530 W 15(th) Street, Lawrence, KS 66045, USA.
  • Tadros M; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA.
  • Khossravi M; Department of Drug Product Development, Bristol-Myers Squibb, Inc., One Squibb Drive, New Brunswick, NJ, 08901, USA.
  • Deshmukh S; Department of Drug Product Development, Bristol-Myers Squibb, Inc., One Squibb Drive, New Brunswick, NJ, 08901, USA.
  • Cheng Y; Department of Discovery Pharmaceutics, Bristol-Myers Squibb, Inc., 3551 Lawrenceville Road, Lawrence Township, NJ, 08648, USA.
  • Joshi SB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA.
  • Volkin DB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA. Electronic address: volkin@ku.edu.
  • Dhar P; Bioengineering Program, School of Engineering, The University of Kansas, 1530 W 15(th) Street, Lawrence, KS 66045, USA; Department of Chemical and Petroleum Engineering, The University of Kansas, 1530 W 15(th) Street, Lawrence, KS 66045, USA. Electronic address: prajnadhar@ku.edu.
J Pharm Sci ; 111(11): 2998-3008, 2022 11.
Article em En | MEDLINE | ID: mdl-35940242
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ultrafiltração / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ultrafiltração / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article