Construction, expression and functional characterization of an engineered antibody against tumor antigen MUC-1C.

Pourjafar, Mona; Miehe, Michaela; Najafi, Rezvan; Soleimani, Meysam; Spillner, Edzard

Pourjafar, Mona; Miehe, Michaela; Najafi, Rezvan; Soleimani, Meysam; Spillner, Edzard.

Afiliação

Pourjafar M; Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; Immunological Biotechnology, Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Miehe M; Immunological Biotechnology, Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark.
Najafi R; Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Soleimani M; Department of Pharmaceutical Biotechnology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: m.soleymani@umsha.ac.ir.
Spillner E; Immunological Biotechnology, Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark. Electronic address: e.spillner@bce.au.dk.

Protein Expr Purif ; 199: 106148, 2022 11.

Article em En | MEDLINE | ID: mdl-35940518

Assuntos

Anticorpos Monoclonais; Anticorpos de Cadeia Única; Antígenos de Neoplasias/genética; Humanos; Imunoterapia; Proteínas Recombinantes/química; Anticorpos de Cadeia Única/genética

Palavras-chave

Breast cancer; Engineered antibody; Mammalian expression; Minibody; Mucin-1; Periplasmic expression

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos de Cadeia Única / Anticorpos Monoclonais Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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