Microglia: Active participants in brain capillary function.
J Cereb Blood Flow Metab
; 42(11): 2161-2163, 2022 11.
Article
em En
| MEDLINE
| ID: mdl-35942567
ABSTRACT
A recent study by Bisht, Okojie, and Sharma, et al. characterizes a population of capillary-associated microglia (CAM) whose cell bodies are positioned along small blood vessels in the healthy mouse brain. Through elegant, longitudinal intravital imaging of brain vasculature and CAMs, the authors have uncovered the significance of microglia in cerebral blood flow regulation. Further investigation into the functions of this CAM population and how they interact with surrounding cells within the neurovascular unit will improve our understanding of vascular regulation and cerebrovascular diseases.
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Base de dados:
MEDLINE
Assunto principal:
Microglia
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Pericitos
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article