Assessing the In Vitro Antioxidant and Anti-inflammatory Activity of Moringa oleifera Crude Extract.
J Contemp Dent Pract
; 23(4): 437-442, 2022 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-35945838
ABSTRACT
BACKGROUND:
Chronic inflammation and oxidative stress play a vital role in the pathogenesis of various diseases of the oral cavity including periodontal disease. Phytochemicals present in plants with antioxidant (AO) and anti-inflammatory properties could aid as a therapeutic adjunct in the management of these diseases.AIM:
To assess the antioxidant and anti-inflammatory effects of aqueous and ethanolic extracts of Moringa oleifera Lam. (MOL) in an in vitro environment. MATERIALS ANDMETHODS:
Aqueous and ethanolic extracts of M. oleifera Lam. were prepared by maceration. Antioxidant activity was assessed by FRAP, hydroxyl radical scavenging activity, and DPPH radical scavenging assay. Anti-inflammatory activity was assessed by Albumin Denaturation Assay. Experiments were repeated thrice, and mean and standard deviation were calculated.RESULTS:
Both the test substances exhibited significant antioxidant and anti-inflammatory activity, and aqueous extracts exhibited higher activity than ethanolic extract. SUMMARY ANDCONCLUSION:
The anti-inflammatory and antioxidant activity of M. oleifera Lam. could be further explored for the management of periodontal disease as a local drug delivery system with the extract could be developed.Palavras-chave
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Doenças Periodontais
/
Moringa oleifera
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article