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A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2-positive) cancer with leptomeningeal metastases: Safety, efficacy, and cerebrospinal fluid pharmacokinetics.
Kumthekar, Priya U; Avram, Michael J; Lassman, Andrew B; Lin, Nancy U; Lee, Eudocia; Grimm, Sean A; Schwartz, Margaret; Bell Burdett, Kirsten L; Lukas, Rimas V; Dixit, Karan; Perron, Isabella; Zhang, Hui; Gradishar, William J; Pentsova, Elena I; Jeyapalan, Suriya; Groves, Morris D; Melisko, Michelle; Raizer, Jeffrey J.
Afiliação
  • Kumthekar PU; Department of Neurology at The Feinberg School of Medicine at Northwestern University and The Malnati Brain Tumor Institute at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
  • Avram MJ; Department of Anesthesiology, Emeritus Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Lassman AB; Division of Neuro-Oncology, Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, Herbert Irving Comprehensive Cancer Center, NewYork-Presbyterian Hospital, New York, New York, USA.
  • Lin NU; Department of Medical Oncology, Dana-Farber Cancer Institute Harvard Medical School, Boston, Massachusetts, USA.
  • Lee E; Department of Medical Oncology, Dana-Farber Cancer Institute Harvard Medical School, Boston, Massachusetts, USA.
  • Grimm SA; Department of Neurology, Rush University Medical Center, Chicago, Illinois, USA.
  • Schwartz M; Department of Neurology at The Feinberg School of Medicine at Northwestern University and The Malnati Brain Tumor Institute at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois.
  • Bell Burdett KL; Department of Preventive Medicine, Division of Biostatistics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Lukas RV; Department of Neurology at The Feinberg School of Medicine at Northwestern University and The Malnati Brain Tumor Institute at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
  • Dixit K; Department of Neurology at The Feinberg School of Medicine at Northwestern University and The Malnati Brain Tumor Institute at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
  • Perron I; Department of Neurosurgery at The Feinberg School of Medicine at Northwestern University, Chicago, Illinois, USA.
  • Zhang H; Department of Preventive Medicine, Division of Biostatistics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Gradishar WJ; Department of Medicine at The Feinberg School of Medicine at Northwestern University at The Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
  • Pentsova EI; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Jeyapalan S; Department of Neurology, Tufts Medical Center, Boston, Massachusetts, USA.
  • Groves MD; Texas Oncology-Austin Brain Tumor Center, Austin, Texas, USA.
  • Melisko M; Department of Medicine at the University of California San Francisco, San Francisco, California, USA.
  • Raizer JJ; Department of Neurology at The Feinberg School of Medicine at Northwestern University and The Malnati Brain Tumor Institute at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
Neuro Oncol ; 25(3): 557-565, 2023 03 14.
Article em En | MEDLINE | ID: mdl-35948282
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Carcinomatose Meníngea Tipo de estudo: Clinical_trials Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Carcinomatose Meníngea Tipo de estudo: Clinical_trials Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article