Biological sample donation and informed consent for neurobiobanking: Evidence from a community survey in Ghana and Nigeria.
PLoS One
; 17(8): e0267705, 2022.
Article
em En
| MEDLINE
| ID: mdl-35951660
ABSTRACT
INTRODUCTION:
Genomic research and neurobiobanking are expanding globally. Empirical evidence on the level of awareness and willingness to donate/share biological samples towards the expansion of neurobiobanking in sub-Saharan Africa is lacking.AIMS:
To ascertain the awareness, perspectives and predictors regarding biological sample donation, sharing and informed consent preferences among community members in Ghana and Nigeria.METHODS:
A questionnaire cross-sectional survey was conducted among randomly selected community members from seven communities in Ghana and Nigeria.RESULTS:
Of the 1015 respondents with mean age 39.3 years (SD 19.5), about a third had heard of blood donation (37.2%, M 42.4%, F 32.0%, p = 0.001) and a quarter were aware of blood sample storage for research (24.5%; M 29.7%, F 19.4%, p = 0.151). Two out of ten were willing to donate brain after death (18.8%, M 22.6%, F 15.0%, p<0.001). Main reasons for unwillingness to donate brain were; to go back to God complete (46.6%) and lack of knowledge related to brain donation (32.7%). Only a third of the participants were aware of informed consent (31.7%; M 35.9%, F 27.5%, p<0.001). Predictors of positive attitude towards biobanking and informed consent were being married, tertiary level education, student status, and belonging to select ethnic groups.CONCLUSION:
There is a greater need for research attention in the area of brain banking and informed consent. Improved context-sensitive public education on neurobiobanking and informed consent, in line with the sociocultural diversities, is recommended within the African sub region.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Obtenção de Tecidos e Órgãos
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Adult
/
Humans
País como assunto:
Africa
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article