Dimethyl Fumarate Induces Apoptosis via Inhibition of NF-&#954;B and Enhances the Effect of Paclitaxel and Adriamycin in Human TNBC Cells.

Tsurushima, Katsumasa; Tsubaki, Masanobu; Takeda, Tomoya; Matsuda, Takuya; Kimura, Akihiro; Takefuji, Honoka; Okada, Akane; Sakamoto, Chiaki; Ishizaka, Toshihiko; Nishida, Shozo

Dimethyl Fumarate Induces Apoptosis via Inhibition of NF-κB and Enhances the Effect of Paclitaxel and Adriamycin in Human TNBC Cells.

Tsurushima, Katsumasa; Tsubaki, Masanobu; Takeda, Tomoya; Matsuda, Takuya; Kimura, Akihiro; Takefuji, Honoka; Okada, Akane; Sakamoto, Chiaki; Ishizaka, Toshihiko; Nishida, Shozo.

Afiliação

Tsurushima K; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Tsubaki M; Sakai City Medical Center, Department of Pharmacy, Sakai 593-8304, Japan.
Takeda T; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Matsuda T; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Kimura A; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Takefuji H; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Okada A; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Sakamoto C; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Ishizaka T; Division of Pharmacotherapy, Faculty of Pharmacy, Kindai University, Kowakae, Higashiosaka 577-8502, Japan.
Nishida S; Sakai City Medical Center, Department of Pharmacy, Sakai 593-8304, Japan.

Int J Mol Sci ; 23(15)2022 Aug 04.

Article em En | MEDLINE | ID: mdl-35955813

Assuntos

NF-kappa B; Neoplasias de Mama Triplo Negativas; Apoptose; Linhagem Celular Tumoral; Proliferação de Células; Fumarato de Dimetilo/farmacologia; Fumarato de Dimetilo/uso terapêutico; Doxorrubicina/farmacologia; Doxorrubicina/uso terapêutico; Humanos; NF-kappa B/metabolismo; Paclitaxel/farmacologia; Paclitaxel/uso terapêutico; Transdução de Sinais; Neoplasias de Mama Triplo Negativas/patologia

Palavras-chave

NF-κB; adriamycin; dimethyl fumarate; paclitaxel; triple-negative breast cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Neoplasias de Mama Triplo Negativas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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