Mechanosensitive cation currents through TRPC6 and Piezo1 channels in human pulmonary arterial endothelial cells.

Zhao, Tengteng; Parmisano, Sophia; Soroureddin, Zahra; Zhao, Manjia; Yung, Lauren; Thistlethwaite, Patricia A; Makino, Ayako; Yuan, Jason X-J

Zhao, Tengteng; Parmisano, Sophia; Soroureddin, Zahra; Zhao, Manjia; Yung, Lauren; Thistlethwaite, Patricia A; Makino, Ayako; Yuan, Jason X-J.

Afiliação

Zhao T; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, California.
Parmisano S; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, California.
Soroureddin Z; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, California.
Zhao M; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, California.
Yung L; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, California.
Thistlethwaite PA; Division of Cardiothoracic Surgery, Department of Surgery, University of California, San Diego, California.
Makino A; Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California.
Yuan JX; Section of Physiology, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, California.

Am J Physiol Cell Physiol ; 323(4): C959-C973, 2022 Oct 01.

Article em En | MEDLINE | ID: mdl-35968892

Assuntos

Células Endoteliais; Canais Iônicos; Mecanorreceptores; Canal de Cátion TRPC6; Cálcio/metabolismo; Cátions/metabolismo; Diglicerídeos/metabolismo; Diglicerídeos/farmacologia; Células Endoteliais/metabolismo; Humanos; Soluções Hipotônicas/metabolismo; Soluções Hipotônicas/farmacologia; Canais Iônicos/genética; Canais Iônicos/metabolismo; Mecanorreceptores/metabolismo; Mecanotransdução Celular/genética; Mecanotransdução Celular/fisiologia; Artéria Pulmonar/citologia; Artéria Pulmonar/metabolismo; Canal de Cátion TRPC6/genética; Canal de Cátion TRPC6/metabolismo

Palavras-chave

calcium; lung vascular endothelial cell; mechanotransduction; nonselective cation channel

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Endoteliais / Canal de Cátion TRPC6 / Canais Iônicos / Mecanorreceptores Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google