A low-power stretchable neuromorphic nerve with proprioceptive feedback.
Nat Biomed Eng
; 7(4): 511-519, 2023 04.
Article
em En
| MEDLINE
| ID: mdl-35970931
ABSTRACT
By relaying neural signals from the motor cortex to muscles, devices for neurorehabilitation can enhance the movement of limbs in which nerves have been damaged as a consequence of injuries affecting the spinal cord or the lower motor neurons. However, conventional neuroprosthetic devices are rigid and power-hungry. Here we report a stretchable neuromorphic implant that restores coordinated and smooth motions in the legs of mice with neurological motor disorders, enabling the animals to kick a ball, walk or run. The neuromorphic implant acts as an artificial efferent nerve by generating electrophysiological signals from excitatory post-synaptic signals and by providing proprioceptive feedback. The device operates at low power (~1/150 that of a typical microprocessor system), and consists of hydrogel electrodes connected to a stretchable transistor incorporating an organic semiconducting nanowire (acting as an artificial synapse), connected via an ion gel to an artificial proprioceptor incorporating a carbon nanotube strain sensor (acting as an artificial muscle spindle). Stretchable electronics with proprioceptive feedback may inspire the further development of advanced neuromorphic devices for neurorehabilitation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Nanotubos de Carbono
/
Retroalimentação Sensorial
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article