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Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.
Arunachalam, Prabhu S; Feng, Yupeng; Ashraf, Usama; Hu, Mengyun; Walls, Alexandra C; Edara, Venkata Viswanadh; Zarnitsyna, Veronika I; Aye, Pyone Pyone; Golden, Nadia; Miranda, Marcos C; Green, Kristyn W M; Threeton, Breanna M; Maness, Nicholas J; Beddingfield, Brandon J; Bohm, Rudolf P; Scheuermann, Sarah E; Goff, Kelly; Dufour, Jason; Russell-Lodrigue, Kasi; Kepl, Elizabeth; Fiala, Brooke; Wrenn, Samuel; Ravichandran, Rashmi; Ellis, Daniel; Carter, Lauren; Rogers, Kenneth; Shirreff, Lisa M; Ferrell, Douglas E; Deb Adhikary, Nihar R; Fontenot, Jane; Hammond, Holly L; Frieman, Matthew; Grifoni, Alba; Sette, Alessandro; O'Hagan, Derek T; Van Der Most, Robbert; Rappuoli, Rino; Villinger, Francois; Kleanthous, Harry; Rappaport, Jay; Suthar, Mehul S; Veesler, David; Wang, Taia T; King, Neil P; Pulendran, Bali.
Afiliação
  • Arunachalam PS; Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, Stanford, CA 94305, USA.
  • Feng Y; Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, Stanford, CA 94305, USA.
  • Ashraf U; Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.
  • Hu M; Institute for Immunity, Transplantation and Infection, School of Medicine, Stanford University, Stanford, CA 94305, USA.
  • Walls AC; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Edara VV; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
  • Zarnitsyna VI; Department of Pediatrics, Emory Vaccine Center, Emory National Primate Research Center, and Emory University School of Medicine, Atlanta, GA 30329, USA.
  • Aye PP; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30329, USA.
  • Golden N; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Miranda MC; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Green KWM; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Threeton BM; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Maness NJ; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Beddingfield BJ; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Bohm RP; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Scheuermann SE; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Goff K; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Dufour J; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Russell-Lodrigue K; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Kepl E; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Fiala B; Tulane National Primate Research Center, Covington, LA 70433, USA.
  • Wrenn S; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Ravichandran R; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Ellis D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Carter L; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Rogers K; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Shirreff LM; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Ferrell DE; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Deb Adhikary NR; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Fontenot J; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Hammond HL; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Frieman M; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • Grifoni A; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.
  • Sette A; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
  • O'Hagan DT; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
  • Van Der Most R; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
  • Rappuoli R; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
  • Villinger F; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
  • Kleanthous H; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Rappaport J; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  • Suthar MS; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, CA 92037, USA.
  • Veesler D; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, CA 92037, USA.
  • Wang TT; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
  • King NP; GSK, Rockville, MD 20850, USA.
  • Pulendran B; GSK, Rixensart 1330, Belgium.
Sci Transl Med ; 14(658): eabq4130, 2022 08 17.
Article em En | MEDLINE | ID: mdl-35976993
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Virais / COVID-19 Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Virais / COVID-19 Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article