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AAV-mediated gene therapy improving mitochondrial function provides benefit in age-related macular degeneration models.
Millington-Ward, Sophia; Chadderton, Naomi; Finnegan, Laura K; Post, Iris J M; Carrigan, Matthew; Gardiner, Tom; Peixoto, Elisa; Maloney, Daniel; Humphries, Marian M; Stitt, Alan; Léveillard, Thierry; Humphries, Pete; Kenna, Paul F; Palfi, Arpad; Farrar, G Jane.
Afiliação
  • Millington-Ward S; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Chadderton N; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Finnegan LK; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Post IJM; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Carrigan M; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Gardiner T; Queen's University Belfast, Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Belfast, UK.
  • Peixoto E; Queen's University Belfast, Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Belfast, UK.
  • Maloney D; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Humphries MM; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Stitt A; Queen's University Belfast, Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Belfast, UK.
  • Léveillard T; Department of Genetics, Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
  • Humphries P; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Kenna PF; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
  • Palfi A; Research Foundation, Royal Victoria Eye and Ear Hospital, Dublin 2, Ireland.
  • Farrar GJ; Smurfit Institute of Genetics, School of Genetics and Microbiology, Trinity College Dublin, Dublin 2, Ireland.
Clin Transl Med ; 12(8): e952, 2022 08.
Article em En | MEDLINE | ID: mdl-35988157
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Degeneração Macular Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia Genética / Degeneração Macular Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article