Direct Transformation of Nitrogen-Containing Methylheteroarenes to Heteroaryl Nitrile by Sodium Nitrite.
Org Lett
; 24(34): 6341-6345, 2022 09 02.
Article
em En
| MEDLINE
| ID: mdl-35993577
ABSTRACT
The cyanation reaction of methylheteroarenes with acetyl chloride and sodium nitrite via the radical process in high yields is reported. According to the control experiments, the reaction mechanism underwent radical progress. It is very useful in the pharmacy industry due to its metal-free and easy treatment conditions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Nitrilas
/
Nitrogênio
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article