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The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages.
Toboz, Phoenix; Amiri, Mehdi; Tabatabaei, Negar; Dufour, Catherine R; Kim, Seung Hyeon; Fillebeen, Carine; Ayemoba, Charles E; Khoutorsky, Arkady; Nairz, Manfred; Shao, Lijian; Pajcini, Kostandin V; Kim, Ki-Wook; Giguère, Vincent; Oliveira, Regiana L; Constante, Marco; Santos, Manuela M; Morales, Carlos R; Pantopoulos, Kostas; Sonenberg, Nahum; Pinho, Sandra; Tahmasebi, Soroush.
Afiliação
  • Toboz P; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612.
  • Amiri M; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Tabatabaei N; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Dufour CR; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612.
  • Kim SH; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Fillebeen C; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612.
  • Ayemoba CE; Lady Davis Institute for Medical Research, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada.
  • Khoutorsky A; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612.
  • Nairz M; Department of Anesthesia and Faculty of Dentistry, McGill University, Montreal, QC, H3A 0G1, Canada.
  • Shao L; Department of Internal Medicine II, Medical University of Innsbruck, Innsbruck, 6020, Austria.
  • Pajcini KV; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612.
  • Kim KW; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612.
  • Giguère V; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612.
  • Oliveira RL; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Constante M; Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada.
  • Santos MM; Department of Anatomy and Cell Biology, McGill University, Montreal, QC, H3G 1Y6, Canada.
  • Morales CR; Nutrition and Microbiome Laboratory, Centre de recherche du CHUM and Department of Medicine, Université de Montréal, Montréal, QC, H3X 0A9, Canada.
  • Pantopoulos K; Nutrition and Microbiome Laboratory, Centre de recherche du CHUM and Department of Medicine, Université de Montréal, Montréal, QC, H3X 0A9, Canada.
  • Sonenberg N; Department of Anatomy and Cell Biology, McGill University, Montreal, QC, H3G 1Y6, Canada.
  • Pinho S; Lady Davis Institute for Medical Research, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC, H3T 1E2, Canada.
  • Tahmasebi S; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.
Proc Natl Acad Sci U S A ; 119(35): e2121251119, 2022 08 30.
Article em En | MEDLINE | ID: mdl-35994670
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Eritrócitos / Aminoácidos / Ferro / Fígado / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Eritrócitos / Aminoácidos / Ferro / Fígado / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article