A flux-based machine learning model to simulate the impact of pathogen metabolic heterogeneity on drug interactions.

Chung, Carolina H; Chandrasekaran, Sriram

Chung, Carolina H; Chandrasekaran, Sriram.

Afiliação

Chung CH; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Chandrasekaran S; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

PNAS Nexus ; 1(3): pgac132, 2022 Jul.

Article em En | MEDLINE | ID: mdl-36016709

Palavras-chave

antibiotic resistance; drug combinations; genome-scale metabolic modeling; heterogeneity; machine learning

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article