Your browser doesn't support javascript.
loading
Critical Care Cardiology Trials Network (CCCTN): a cohort profile.
Metkus, Thomas S; Baird-Zars, Vivian M; Alfonso, Carlos E; Alviar, Carlos L; Barnett, Christopher F; Barsness, Gregory W; Berg, David D; Bertic, Mia; Bohula, Erin A; Burke, James; Burstein, Barry; Chaudhry, Sunit-Preet; Cooper, Howard A; Daniels, Lori B; Fordyce, Christopher B; Ghafghazi, Shahab; Goldfarb, Michael; Katz, Jason N; Keeley, Ellen C; Keller, Norma M; Kenigsberg, Benjamin; Kontos, Michael C; Kwon, Younghoon; Lawler, Patrick R; Leibner, Evan; Liu, Shuangbo; Menon, Venu; Miller, P Elliott; Newby, L Kristin; O'Brien, Connor G; Papolos, Alexander I; Pierce, Matthew J; Prasad, Rajnish; Pisani, Barbara; Potter, Brian J; Roswell, Robert O; Sinha, Shashank S; Shah, Kevin S; Smith, Timothy D; Snell, R Jeffrey; So, Derek; Solomon, Michael A; Ternus, Bradley W; Teuteberg, Jeffrey J; van Diepen, Sean; Zakaria, Sammy; Morrow, David A.
Afiliação
  • Metkus TS; Divisions of Cardiology and Cardiac Surgery, Departments of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Baird-Zars VM; Levine Cardiac Intensive Care Unit, TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Alfonso CE; Division of Cardiology, Department of Medicine; University of Miami Hospital & Clinics, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  • Alviar CL; Leon H. Charney Division of Cardiology, NYU Langone Medical Center, New York 10016 NY, USA.
  • Barnett CF; Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
  • Barsness GW; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55902, USA.
  • Berg DD; Levine Cardiac Intensive Care Unit, TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Bertic M; University of Toronto Etobicoke,Toronto ON, Canada.
  • Bohula EA; Levine Cardiac Intensive Care Unit, TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Burke J; Lehigh Valley Heart Institute, Allentown, PA 18103, USA.
  • Burstein B; University of Toronto, Toronto, ON, Canada.
  • Chaudhry SP; StVincent Heart Center, Indianapolis, IN 46260, USA.
  • Cooper HA; Westchester Medical Center and New York Medical College, Valhalla NY 10901, USA.
  • Daniels LB; Division of Cardiovascular Medicine La Jolla, UCSD, San Diego, CA 92037, USA.
  • Fordyce CB; UBC Centre for Cardiovascular Innovation, Cardiovascular Health Program, UBC Centre for Health Evaluation & Outcomes Sciences, University of British Columbia, Vancouver, BC, Canada.
  • Ghafghazi S; Division of Cardiovascular Medicine, University of Louisville, Louisville, KY 40202, USA.
  • Goldfarb M; Division of Cardiology, Jewish General Hospital, McGill University, Montréal, QC, Canada.
  • Katz JN; Division of Cardiology, Duke University School of Medicine, Durham, NC 27710, USA.
  • Keeley EC; Division of Cardiology, Department of Medicine, University of Florida, Gainesville, FL 32610, USA.
  • Keller NM; Department of Medicine at NYU Grossman School of Medicine, Bellevue Hospital, New York NY 10016, USA.
  • Kenigsberg B; Departments of Cardiology and Critical Care Medicine, MedStar Washington Hospital Center, Washington DC, WA 20010, USA.
  • Kontos MC; Division of Cardiology, Virginia Commonwealth University, Richmond, VA 23219, USA.
  • Kwon Y; Division of Cardiology, University of Washington, Seattle, WA 98104, USA.
  • Lawler PR; Peter Munk Cardiac Centre, Toronto General Hospital, University of Toronto, Toronto ON, Canada.
  • Leibner E; Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, The Mount Sinai Hospital, New York, NY 10029, USA.
  • Liu S; Max Rady College of Medicine St. Boniface Hospital Winnipeg, Manitoba, Canada.
  • Menon V; Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
  • Miller PE; Department of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
  • Newby LK; Divison of Cardiology, Duke University School of Medicine, Durham, NC 27710, USA.
  • O'Brien CG; Department of Medicine, Division of Cardiology, University of California-San Francisco School of Medicine, San Francisco, CA 94143, USA.
  • Papolos AI; Departments of Cardiology and Critical Care Medicine, MedStar Washington Hospital Center, Washington DC, WA 20010, USA.
  • Pierce MJ; Department of Cardiology, Zucker School of Medicine at Hofstra/Northwell, Long Island, NY 11549, USA.
  • Prasad R; Wellstar Cardiovascular Medicine, Marietta, GA 30060, USA.
  • Pisani B; Atrium Wake Forest Baptist Winston-Salem, NC 27157, USA.
  • Potter BJ; Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
  • Roswell RO; Lenox Hospital, Northwell Health, New York, NY 10075, USA.
  • Sinha SS; Inova Heart and Vascular Institute, Inova Fairfax Medical Center, Falls Church, VA 22042, USA.
  • Shah KS; University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.
  • Smith TD; The Christ Hospital and Lindner Institute for Research and Education Cincinnati, OH 45219, USA.
  • Snell RJ; Rush University Medical Center, Chicago IL 60612, USA.
  • So D; University of Ottawa Heart Institute, Ottawa, ON, Canada.
  • Solomon MA; University of Toronto, Toronto, ON, Canada.
  • Ternus BW; Division of Cardiology, Department of Internal Medicine, University of Wisconsin, Madison, WI 53792, USA.
  • Teuteberg JJ; Division of Cardiovascular Medicine, Stanford University Medical Center, Palo Alto, CA 94305, USA.
  • van Diepen S; Division of Cardiology, Department of Critical Care Medicine, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
  • Zakaria S; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Morrow DA; Levine Cardiac Intensive Care Unit, TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Eur Heart J Qual Care Clin Outcomes ; 8(7): 703-708, 2022 10 26.
Article em En | MEDLINE | ID: mdl-36029517
ABSTRACT

AIMS:

The aims of the Critical Care Cardiology Trials Network (CCCTN) are to develop a registry to investigate the epidemiology of cardiac critical illness and to establish a multicentre research network to conduct randomised clinical trials (RCTs) in patients with cardiac critical illness. METHODS AND

RESULTS:

The CCCTN was founded in 2017 with 16 centres and has grown to a research network of over 40 academic and clinical centres in the United States and Canada. Each centre enters data for consecutive cardiac intensive care unit (CICU) admissions for at least 2 months of each calendar year. More than 20 000 unique CICU admissions are now included in the CCCTN Registry. To date, scientific observations from the CCCTN Registry include description of variations in care, the epidemiology and outcomes of all CICU patients, as well as subsets of patients with specific disease states, such as shock, heart failure, renal dysfunction, and respiratory failure. The CCCTN has also characterised utilization patterns, including use of mechanical circulatory support in response to changes in the heart transplantation allocation system, and the use and impact of multidisciplinary shock teams. Over years of multicentre collaboration, the CCCTN has established a robust research network to facilitate multicentre registry-based randomised trials in patients with cardiac critical illness.

CONCLUSION:

The CCCTN is a large, prospective registry dedicated to describing processes-of-care and expanding clinical knowledge in cardiac critical illness. The CCCTN will serve as an investigational platform from which to conduct randomised controlled trials in this important patient population.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiologia / Estado Terminal Tipo de estudo: Clinical_trials / Risk_factors_studies Limite: Humans País como assunto: America do norte Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiologia / Estado Terminal Tipo de estudo: Clinical_trials / Risk_factors_studies Limite: Humans País como assunto: America do norte Idioma: En Ano de publicação: 2022 Tipo de documento: Article