Eight new arnebinol B-based meroterpenoids with planar chirality in the constrained 6/10/5 tricyclic skeleton from Arnebia euchroma and their cytotoxicities.

Yan, Hai-Wei; Yang, Ya-Nan; Zhang, Xu; Jiang, Jian-Shuang; Yuan, Xiang; Feng, Zi-Ming; Zhang, Pei-Cheng

Yan, Hai-Wei; Yang, Ya-Nan; Zhang, Xu; Jiang, Jian-Shuang; Yuan, Xiang; Feng, Zi-Ming; Zhang, Pei-Cheng.

Afiliação

Yan HW; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Yang YN; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zhang X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Jiang JS; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Yuan X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Feng ZM; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zhang PC; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: pczhang@imm.ac.cn.

Bioorg Chem ; 128: 106091, 2022 11.

Article em En | MEDLINE | ID: mdl-36029650

Assuntos

Boraginaceae; Boraginaceae/química; Estrutura Molecular; Raízes de Plantas/química; Esqueleto; Terpenos/química; Terpenos/farmacologia

Palavras-chave

6/10/5 tricyclic meroterpenoids; Arnebia euchroma; Cytotoxicity; Planar chirality

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Boraginaceae Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Boraginaceae Idioma: En Ano de publicação: 2022 Tipo de documento: Article