Studies of carbohydrate-carbohydrate-interactions by atomic force microscopy employing functionalized 4-acetylthio-butyl glucopyranosides.
Carbohydr Res
; 521: 108649, 2022 Nov.
Article
em En
| MEDLINE
| ID: mdl-36037650
ABSTRACT
By Fischer glycosylation both anomers of 4-chlorobutyl gluco-as well as galactopyranosides were obtained and transformed into the corresponding 4-acetylthio-butyl glycopyranosides. Dependent on the precursors two straightforward routes were followed to obtain the appropriate 3-O-sulfated derivatives. Unsubstituted and sulfated glucopyranosides were attached to gold surfaces a gold tips. Their interactions were studied using atomic force microscopy for simulations of intercellular glycoside-based interactions and discussed in-depth.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Glicosídeos
/
Ouro
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article