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DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting.
Yuskaitis, Christopher J; Modasia, Jinita B; Schrötter, Sandra; Rossitto, Leigh-Ana; Groff, Karenna J; Morici, Christopher; Mithal, Divakar S; Chakrabarty, Ram P; Chandel, Navdeep S; Manning, Brendan D; Sahin, Mustafa.
Afiliação
  • Yuskaitis CJ; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Division of Epilepsy and Clinical Neurophysiology and Epilepsy Genetics Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Modasia JB; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Schrötter S; Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Rossitto LA; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Groff KJ; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Morici C; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Mithal DS; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Section of Neurology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
  • Chakrabarty RP; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Chandel NS; Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Manning BD; Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Sahin M; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA. Ele
Cell Rep ; 40(9): 111278, 2022 08 30.
Article em En | MEDLINE | ID: mdl-36044864

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Jejum / Proteínas Ativadoras de GTPase / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Jejum / Proteínas Ativadoras de GTPase / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article