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Lead Optimization of Nerve-Specific Fluorophores for Image-Guided Nerve Sparing Surgical Procedures.
Barth, Connor W; Wang, Lei G; Montano, Antonio; Antaris, Alexander L; Klaassen, Alwin; Sorger, Jonathan; Kerr, Darcy A; Henderson, Eric R; Alani, Adam W G; Gibbs, Summer L.
Afiliação
  • Barth CW; Inherent Targeting, Portland, OR, 97201.
  • Wang LG; Biomedical Engineering Department, Oregon Health & Science University, Portland, OR 97201.
  • Montano A; Biomedical Engineering Department, Oregon Health & Science University, Portland, OR 97201.
  • Antaris AL; Intuitive Surgical, Sunnyvale, CA 94086.
  • Klaassen A; Intuitive Surgical, Sunnyvale, CA 94086.
  • Sorger J; Intuitive Surgical, Sunnyvale, CA 94086.
  • Kerr DA; Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.
  • Henderson ER; Geisel School of Medicine at Dartmouth College, Hanover, NH 03755.
  • Alani AWG; Department of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.
  • Gibbs SL; Biomedical Engineering Department, Oregon Health & Science University, Portland, OR 97201.
Article em En | MEDLINE | ID: mdl-36053248
ABSTRACT
Nerve damage is a major complication of surgery, causing pain and loss of function. We have identified novel near-infrared nerve-specific fluorophores that provide excellent nerve contrast with the ability to identify buried nerve tissue.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article