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[Advances and Application of Genomics in Chronic Obstructive Pulmonary Disease].
Su, Lin-Fan; Zhao, Hong-Mei; Xiao, Yi.
Afiliação
  • Su LF; Department of Respiratory and Critical Care Medicine,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
  • Zhao HM; State Key Laboratory of Medical Molecular Biology,Department of Pathophysiology,Institute of Basic Medical Sciences, CAMS and PUMC,Beijing 100005,China.
  • Xiao Y; Department of Respiratory and Critical Care Medicine,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 44(4): 668-672, 2022 Aug.
Article em Zh | MEDLINE | ID: mdl-36065700
Chronic obstructive pulmonary disease (COPD) is a common and frequently-occurring disease in the department of respiratory medicine,the pathogenesis of which involves both environmental factors and genetic factors.In recent years,with the application of new methods such as genome-wide association study,researchers have discovered a large number of gene mutations associated with lung function and COPD,providing a new perspective on the pathogenesis of COPD and potential therapeutic targets.This article reviews the research achievements and application progress of genomics in COPD.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença Pulmonar Obstrutiva Crônica / Estudo de Associação Genômica Ampla Limite: Humans Idioma: Zh Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença Pulmonar Obstrutiva Crônica / Estudo de Associação Genômica Ampla Limite: Humans Idioma: Zh Ano de publicação: 2022 Tipo de documento: Article