Targeting cancer stem cells in the tumor microenvironment: An emerging role of PARP inhibitors.

Paul, Subarno; Sinha, Saptarshi; Kundu, Chanakya Nath

Paul, Subarno; Sinha, Saptarshi; Kundu, Chanakya Nath.

Afiliação

Paul S; Cancer Biology Division, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Campus-11, Patia, Bhubaneswar, Odisha 751024, India.
Sinha S; Cancer Biology Division, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Campus-11, Patia, Bhubaneswar, Odisha 751024, India.
Kundu CN; Cancer Biology Division, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Deemed to be University, Campus-11, Patia, Bhubaneswar, Odisha 751024, India. Electronic address: cnkundu@kiitbiotech.ac.in.

Pharmacol Res ; 184: 106425, 2022 10.

Article em En | MEDLINE | ID: mdl-36075511

Assuntos

Neoplasias; Inibidores de Poli(ADP-Ribose) Polimerases; Cromatina/metabolismo; Resistencia a Medicamentos Antineoplásicos; Humanos; Neoplasias/metabolismo; Células-Tronco Neoplásicas; Inibidores de Poli(ADP-Ribose) Polimerases/farmacologia; Inibidores de Poli(ADP-Ribose) Polimerases/uso terapêutico; Microambiente Tumoral

Palavras-chave

Cancer stem cells; DNA repair; Drug resistance; Epigenetic modifications; PARP inhibitors; PARP1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Poli(ADP-Ribose) Polimerases / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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