Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.

Li, Xiaoman; Pan, Yongbing; Yin, Qiangling; Wang, Zejun; Shan, Sisi; Zhang, Laixing; Yu, Jinfang; Qu, Yuanyuan; Sun, Lina; Gui, Fang; Lu, Jia; Jing, Zhaofei; Wu, Wei; Huang, Tao; Shi, Xuanling; Li, Jiandong; Li, Xinguo; Li, Dexin; Wang, Shiwen; Yang, Maojun; Zhang, Linqi; Duan, Kai; Liang, Mifang; Yang, Xiaoming; Wang, Xinquan

Li, Xiaoman; Pan, Yongbing; Yin, Qiangling; Wang, Zejun; Shan, Sisi; Zhang, Laixing; Yu, Jinfang; Qu, Yuanyuan; Sun, Lina; Gui, Fang; Lu, Jia; Jing, Zhaofei; Wu, Wei; Huang, Tao; Shi, Xuanling; Li, Jiandong; Li, Xinguo; Li, Dexin; Wang, Shiwen; Yang, Maojun; Zhang, Linqi; Duan, Kai; Liang, Mifang; Yang, Xiaoming; Wang, Xinquan.

Afiliação

Li X; The Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, China.
Pan Y; National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
Yin Q; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Wang Z; National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
Shan S; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Zhang L; The Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, China.
Yu J; The Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, China.
Qu Y; Institution of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
Sun L; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Gui F; National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
Lu J; National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
Jing Z; National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
Wu W; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Huang T; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Shi X; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Li J; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Li X; National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
Li D; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Wang S; CDC-WIV Joint Research Center for Emerging Diseases and Biosafety, Wuhan, Hubei, China.
Yang M; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhang L; CDC-WIV Joint Research Center for Emerging Diseases and Biosafety, Wuhan, Hubei, China.
Duan K; The Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, China.
Liang M; NexVac Research Center, Comprehensive AIDS Research Center, Center for Infectious Disease Research, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, China.
Yang X; National Engineering Technology Research Center for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
Wang X; State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. liangmf@ivdc.chinacdc.cn.

Cell Discov ; 8(1): 87, 2022 Sep 08.

Article em En | MEDLINE | ID: mdl-36075908

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article