Anti-Inflammatory Action of Dexmedetomidine on Human Microglial Cells.

Yamazaki, Sho; Yamaguchi, Keisuke; Someya, Akimasa; Nagaoka, Isao; Hayashida, Masakazu

Yamazaki, Sho; Yamaguchi, Keisuke; Someya, Akimasa; Nagaoka, Isao; Hayashida, Masakazu.

Afiliação

Yamazaki S; Department of Anesthesiology and Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan.
Yamaguchi K; Department of Anesthesiology and Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan.
Someya A; Department of Anesthesiology and Pain Medicine, Juntendo Tokyo Koto Geriatric Medical Center, 3-3-20 Shinsuna, Koto-Ku, Tokyo 136-0075, Japan.
Nagaoka I; Department of Biochemistry and Systems Biomedicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan.
Hayashida M; Department of Biochemistry and Systems Biomedicine, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo 113-8421, Japan.

Int J Mol Sci ; 23(17)2022 Sep 03.

Article em En | MEDLINE | ID: mdl-36077505

Assuntos

Delírio; Dexmedetomidina; Anti-Inflamatórios/farmacologia; Citocinas; Dexmedetomidina/farmacologia; Humanos; Proteínas I-kappa B; Interleucina-6; Interleucina-8; Lipopolissacarídeos/farmacologia; Microglia; NF-kappa B; Proteínas Quinases p38 Ativadas por Mitógeno

Palavras-chave

anti-inflammatory action; cytokine; delirium; dexmedetomidine; microglia; signaling molecule

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dexmedetomidina / Delírio Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dexmedetomidina / Delírio Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article