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Targeting the PTP1B-Bcr-Abl1 interaction for the degradation of T315I mutant Bcr-Abl1 in chronic myeloid leukemia.
Elgehama, Ahmed; Wang, Yixuan; Yu, Ying; Zhou, Lin; Chen, Zhixiu; Wang, Liwei; Sun, Lijun; Gao, Jian; Yu, Biao; Shen, Yan; Xu, Qiang.
Afiliação
  • Elgehama A; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Yu Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Zhou L; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Chen Z; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Wang L; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Sun L; Department of Chemistry, University of Science and Technology of China, Hefei, China.
  • Gao J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Yu B; State Key Laborary of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Academy, Shanghai, China.
  • Shen Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
  • Xu Q; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Cancer Sci ; 114(1): 247-258, 2023 Jan.
Article em En | MEDLINE | ID: mdl-36086954
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Inibidores de Proteínas Quinases Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Inibidores de Proteínas Quinases Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article