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Adagrasib, a KRAS G12C inhibitor, reverses the multidrug resistance mediated by ABCB1 in vitro and in vivo.
Zhang, Yuchen; Li, Cheukfai; Xia, Chenglai; Wah To, Keneth Kin; Guo, Zhixing; Ren, Chongyang; Wen, Lingzhu; Wang, Fang; Fu, Liwu; Liao, Ning.
Afiliação
  • Zhang Y; School of Medicine, South China University of Technology, Guangzhou, 510006, Guangdong Province, China.
  • Li C; Collaborative Innovation Center for Cancer Medicine; State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute; Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
  • Xia C; Department of Breast Cancer, Department of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong Province, China.
  • Wah To KK; Department of Breast Cancer, Department of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong Province, China.
  • Guo Z; Foshan Women and Children's Hospital Affiliated to Southern Medical University, Foshan, 528000, China.
  • Ren C; School of Pharmacy, The Chinese University of Hong Kong, Hong Kong, 999077, China.
  • Wen L; Collaborative Innovation Center for Cancer Medicine; State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute; Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
  • Wang F; Department of Breast Cancer, Department of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong Province, China.
  • Fu L; Department of Breast Cancer, Department of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong Province, China.
  • Liao N; Collaborative Innovation Center for Cancer Medicine; State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute; Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China.
Cell Commun Signal ; 20(1): 142, 2022 09 14.
Article em En | MEDLINE | ID: mdl-36104708
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article