METTL3-mediated m6A mRNA contributes to the resistance of carbon-ion radiotherapy in non-small-cell lung cancer.

Xu, Xiaofeng; Zhang, Peiru; Huang, Yangle; Shi, Weizhong; Mao, Jingfang; Ma, Ningyi; Kong, Lin; Guo, Lin; Liu, Jinlong; Chen, Jian; Lu, Renquan

Xu, Xiaofeng; Zhang, Peiru; Huang, Yangle; Shi, Weizhong; Mao, Jingfang; Ma, Ningyi; Kong, Lin; Guo, Lin; Liu, Jinlong; Chen, Jian; Lu, Renquan.

Afiliação

Xu X; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhang P; Department of Clinical Laboratory, Shanghai Proton and Heavy Ion Center, Shanghai, China.
Huang Y; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China.
Shi W; Department of Radiation Oncology, Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai Proton and Heavy Ion Center, Shanghai, China.
Mao J; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China.
Ma N; Department of Radiation Oncology, Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai Proton and Heavy Ion Center, Shanghai, China.
Kong L; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Guo L; Department of Radiation Oncology, Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai Proton and Heavy Ion Center, Shanghai, China.
Liu J; Department of Radiation Oncology, Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai Proton and Heavy Ion Center, Shanghai, China.
Chen J; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Lu R; Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China.

Cancer Sci ; 114(1): 105-114, 2023 Jan.

Article em En | MEDLINE | ID: mdl-36114749

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Humanos; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/radioterapia; Metiltransferases/genética; Metiltransferases/metabolismo; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/radioterapia; Carbono

Palavras-chave

H2AX; N6-methyladenosine; carbon-ion radiotherapy; methyltransferase-like 3; non-small-cell lung cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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