N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances.

Salazar-González, Raúl A; Doll, Mark A; Hein, David W

Salazar-González, Raúl A; Doll, Mark A; Hein, David W.

Afiliação

Salazar-González RA; Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, 505 S. Hancock Street, CTR Rm 303, Louisville, KY, 40202, USA.
Doll MA; Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, 505 S. Hancock Street, CTR Rm 303, Louisville, KY, 40202, USA.
Hein DW; Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, 505 S. Hancock Street, CTR Rm 303, Louisville, KY, 40202, USA. david.hein@louisville.edu.

Arch Toxicol ; 97(1): 189-199, 2023 01.

Article em En | MEDLINE | ID: mdl-36138126

Assuntos

Arilamina N-Acetiltransferase; Carcinógenos; Cricetinae; Animais; Humanos; Adolescente; Cricetulus; Células CHO; Carcinógenos/toxicidade; Espécies Reativas de Oxigênio; Dano ao DNA; Arilamina N-Acetiltransferase/genética; Arilamina N-Acetiltransferase/metabolismo; Acetiltransferases/genética; Estresse Oxidativo; Polimorfismo Genético; Acetilação

Palavras-chave

DNA damage; N-acetylation polymorphism; N-acetyltransferase 2; New Psychoactive Substances; Oxidative damage

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arilamina N-Acetiltransferase / Carcinógenos Limite: Adolescent / Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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