Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.

Ramms, Bastian; Pollow, Dennis P; Zhu, Han; Nora, Chelsea; Harrington, Austin R; Omar, Ibrahim; Gordts, Philip L S M; Wortham, Matthew; Sander, Maike

Ramms, Bastian; Pollow, Dennis P; Zhu, Han; Nora, Chelsea; Harrington, Austin R; Omar, Ibrahim; Gordts, Philip L S M; Wortham, Matthew; Sander, Maike.

Afiliação

Ramms B; Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA.
Pollow DP; Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA.
Zhu H; Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA.
Nora C; Department of Medicine, University of California, San Diego, La Jolla, CA.
Harrington AR; Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA.
Omar I; Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA.
Gordts PLSM; Department of Medicine, University of California, San Diego, La Jolla, CA.
Wortham M; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA.
Sander M; Departments of Pediatrics and Cellular and Molecular Medicine, Pediatric Diabetes Research Center, University of California, San Diego, La Jolla, CA.

Diabetes ; 71(12): 2513-2529, 2022 12 01.

Article em En | MEDLINE | ID: mdl-36162056

Assuntos

Diabetes Mellitus Tipo 2; Resistência à Insulina; Hepatopatia Gordurosa não Alcoólica; Camundongos; Animais; Lisina/metabolismo; Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico; Hepatopatia Gordurosa não Alcoólica/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; Obesidade/tratamento farmacológico; Obesidade/metabolismo; Insulina/metabolismo; Histona Desmetilases/metabolismo; Inflamação/metabolismo; Lipídeos; Metabolismo dos Lipídeos; Camundongos Endogâmicos C57BL; Fígado/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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