Regional epithelial cell diversity in the small intestine of pigs.
J Anim Sci
; 1012023 Jan 03.
Article
em En
| MEDLINE
| ID: mdl-36183288
Cells lining the intestinal tract (i.e., epithelial cells) provide a barrier to the outside environment but also play important specialized roles in nutrient absorption and secretion of mucus or hormones involved in controlling appetite and digestion. While similar cell types can be found throughout the small intestine, they have even more specialized function depending on region of the small intestine. Identification and characterization of intestinal epithelial cells are foundational to promoting pig intestinal health for optimal growth. Our research identified six types of epithelial cells across the small intestine of pigs. Enterocytes, an absorptive cell type, shared commonalities with human enterocytes, but a population of enteroendocrine cells, which secrete hormones, was unique to pigs. The location of certain epithelial cells in the intestine was identified and informed the relationship between various epithelial cell types. Overall, a clearer understanding of specific epithelial cells in the porcine intestine is provided, proving a critical foundation to further research aimed at maximizing pig intestinal health.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Duodeno
/
Intestino Delgado
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article