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A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos.
Liu, Yuan; Chudgar, Neel; Mastrogiacomo, Brooke; He, Di; Lankadasari, Manendra B; Bapat, Samhita; Jones, Gregory D; Sanchez-Vega, Francisco; Tan, Kay See; Schultz, Nikolaus; Mukherjee, Semanti; Offit, Kenneth; Bao, Yongde; Bott, Matthew J; Rekhtman, Natasha; Adusumilli, Prasad S; Li, Bob T; Mayo, Marty W; Jones, David R.
Afiliação
  • Liu Y; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Chudgar N; Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Mastrogiacomo B; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • He D; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Lankadasari MB; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Bapat S; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Jones GD; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Sanchez-Vega F; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Tan KS; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Schultz N; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Mukherjee S; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Offit K; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Bao Y; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Bott MJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Rekhtman N; Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA.
  • Adusumilli PS; Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Li BT; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Mayo MW; Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Jones DR; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Sci Transl Med ; 14(665): eabo1050, 2022 10 05.
Article em En | MEDLINE | ID: mdl-36197962
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article