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COVID-19 vaccination may enhance hippocampal neurogenesis in adults.
Kumar, Ashutosh; Narayan, Ravi K; Prasoon, Pranav; Jha, Rakesh K; Kumar, Sujeet; Kumari, Chiman; Pandey, Sada N; Faiq, Muneeb A.
Afiliação
  • Kumar A; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; Department of Anatomy, All India Institute of Medical Sciences (AIIMS), Patna, India. Electronic address: drashutoshkumar@aiimspatna.org.
  • Narayan RK; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; Department of Anatomy, Dr. B.C. Roy Multi Speciality Medical Research Centre, Indian Institute of Technology, Kharagpur, India.
  • Prasoon P; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; Pittsburgh Center for Pain Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Jha RK; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; Department of Anatomy, All India Institute of Medical Sciences (AIIMS), Patna, India.
  • Kumar S; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; Centre for Proteomics and Drug Discovery, Amity Institute of Biotechnology, Amity University, Maharashtra, India.
  • Kumari C; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; Department of Anatomy, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
  • Pandey SN; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; Department of Zoology, Banaras Hindu University (BHU), Varanasi, India.
  • Faiq MA; Etiologically Elusive Disorders Research Network (EEDRN), New Delhi, India; New York University (NYU) Langone Health Center, NYU Robert I Grossman School of Medicine, New York, NY, USA.
Brain Behav Immun ; 107: 87-89, 2023 01.
Article em En | MEDLINE | ID: mdl-36202167
Emerging evidence suggests a detrimental impact of COVID-19 illness on the continued hippocampal neurogenesis in adults. In contrast, the existing literature supports an enhancing effect of COVID-19 vaccination on adult hippocampal neurogenesis. Vaccines against respiratory infections, including influenza, have been shown to enhance hippocampal neurogenesis in adult-age animals. We propose that a similar benefit may happen in COVID-19 vaccinated adults. The vaccine-induced enhancement of the hippocampal neurogenesis in adults thus may protect against age-related cognitive decline and mental disorders. It alsohints at an added mental health benefit of the COVID-19 vaccination programs in adults.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article