A Theranostic Approach for CAR-T Cell Therapy.

Weber, Wolfgang A; Varasteh, Zohreh; Fritschle, Katja; Morath, Volker

Weber, Wolfgang A; Varasteh, Zohreh; Fritschle, Katja; Morath, Volker.

Afiliação

Weber WA; Department of Nuclear Medicine, Technical University of Munich, Munich, Germany.
Varasteh Z; Department of Nuclear Medicine, Technical University of Munich, Munich, Germany.
Fritschle K; Department of Nuclear Medicine, University of Essen, Essen, Germany.
Morath V; Department of Nuclear Medicine, Technical University of Munich, Munich, Germany.

Clin Cancer Res ; 28(24): 5241-5243, 2022 12 15.

Article em En | MEDLINE | ID: mdl-36250927

ABSTRACT

ABSTRACT

Fibroblast activation protein (FAP) is frequently expressed in the tumor stroma, whereas expression by normal organs is highly restricted. Despite these promising features, FAP-targeted therapies have shown limited success so far. FAP imaging offers new opportunities to select patients for FAP-targeted therapies and monitor tumor response. See related article by Lee et al., p. 5330.

Assuntos

Gelatinases; Receptores de Antígenos Quiméricos; Humanos; Gelatinases/genética; Serina Endopeptidases; Receptores de Antígenos Quiméricos/metabolismo; Medicina de Precisão; Endopeptidases; Linhagem Celular Tumoral; Proteínas de Membrana/metabolismo; Linfócitos T/metabolismo; Terapia Baseada em Transplante de Células e Tecidos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gelatinases / Receptores de Antígenos Quiméricos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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