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Urine Tenofovir Levels Strongly Correlate With Virologic Suppression in Patients With Human Immunodeficiency Virus on Tenofovir Alafenamide-Based Antiretroviral Therapy.
Johnson, Kelly A; Okochi, Hideaki; Arreguin, Mireya; Watabe, Joseph; Glidden, David V; Chattopadhyay, Anindita; Imbert, Elizabeth; Hickey, Matthew D; Gandhi, Monica; Spinelli, Matthew.
Afiliação
  • Johnson KA; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Okochi H; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Arreguin M; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Watabe J; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Glidden DV; Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, California, USA.
  • Chattopadhyay A; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Imbert E; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Hickey MD; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Gandhi M; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
  • Spinelli M; Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Clin Infect Dis ; 76(5): 930-933, 2023 03 04.
Article em En | MEDLINE | ID: mdl-36253952
ABSTRACT
We found that urine tenofovir (TFV) levels >1500 ng/mL strongly predict virologic suppression among people with human immunodeficiency virus taking tenofovir alafenamide (odds ratio, 5.66; 95% confidence interval, 1.59-20.14; P = .007). This suggests an existing point-of-care assay developed for tenofovir disoproxil fumarate will support adherence monitoring for patients on all TFV-based antiretrovirals.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Fármacos Anti-HIV Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / HIV-1 / Fármacos Anti-HIV Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article