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Modular robotic platform for precision neurosurgery with a bio-inspired needle: System overview and first in-vivo deployment.
Secoli, Riccardo; Matheson, Eloise; Pinzi, Marlene; Galvan, Stefano; Donder, Abdulhamit; Watts, Thomas; Riva, Marco; Zani, Davide Danilo; Bello, Lorenzo; Rodriguez Y Baena, Ferdinando.
Afiliação
  • Secoli R; The Mechatronics in Medicine Lab, Department of Mechanical Engineering, Imperial College London, London, United Kingdom.
  • Matheson E; The Mechatronics in Medicine Lab, Department of Mechanical Engineering, Imperial College London, London, United Kingdom.
  • Pinzi M; The Mechatronics in Medicine Lab, Department of Mechanical Engineering, Imperial College London, London, United Kingdom.
  • Galvan S; The Mechatronics in Medicine Lab, Department of Mechanical Engineering, Imperial College London, London, United Kingdom.
  • Donder A; The Mechatronics in Medicine Lab, Department of Mechanical Engineering, Imperial College London, London, United Kingdom.
  • Watts T; The Mechatronics in Medicine Lab, Department of Mechanical Engineering, Imperial College London, London, United Kingdom.
  • Riva M; Department of Biomedical Sciences, Humanitas University, Milan, Italy.
  • Zani DD; Istituto di Ricovero e Cura a Carattere Scientifico Humanitas Research Hospital Rozzano, Rozzano, Italy.
  • Bello L; Department of Veterinary Medicine, Universitá degli Studi di Milano, Lodi, Italy.
  • Rodriguez Y Baena F; Department of Oncology and Hematology-Oncology, Universitá degli Studi di Milano, Milan, Italy.
PLoS One ; 17(10): e0275686, 2022.
Article em En | MEDLINE | ID: mdl-36260553
ABSTRACT
Over the past 10 years, minimally invasive surgery (MIS) has shown significant benefits compared to conventional surgical techniques, with reduced trauma, shorter hospital stays, and shorter patient recovery times. In neurosurgical MIS procedures, inserting a straight tool (e.g. catheter) is common practice in applications ranging from biopsy and laser ablation, to drug delivery and fluid evacuation. How to handle tissue deformation, target migration and access to deep-seated anatomical structures remain an open challenge, affecting both the preoperative planning phase and eventual surgical intervention. Here, we present the first neurosurgical platform in the literature, able to deliver an implantable steerable needle for a range of diagnostic and therapeutic applications, with a short-term focus on localised drug delivery. This work presents the system's architecture and first in vivo deployment with an optimised surgical workflow designed for pre-clinical trials with the ovine model, which demonstrate appropriate function and safe implantation.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Robótica / Procedimentos Cirúrgicos Robóticos / Neurocirurgia Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Robótica / Procedimentos Cirúrgicos Robóticos / Neurocirurgia Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article