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Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.
Juette, Manuel F; Carelli, Jordan D; Rundlet, Emily J; Brown, Alan; Shao, Sichen; Ferguson, Angelica; Wasserman, Michael R; Holm, Mikael; Taunton, Jack; Blanchard, Scott C.
Afiliação
  • Juette MF; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, United States.
  • Carelli JD; Chemistry and Chemical Biology Graduate Program, University of California, San Francisco, San Francisco, United States.
  • Rundlet EJ; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, United States.
  • Brown A; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, United States.
  • Shao S; Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medicine, New York, United States.
  • Ferguson A; MRC-LMB, Francis Crick Avenue, Cambridge, United Kingdom.
  • Wasserman MR; MRC-LMB, Francis Crick Avenue, Cambridge, United Kingdom.
  • Holm M; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, United States.
  • Taunton J; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, United States.
  • Blanchard SC; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, United States.
Elife ; 112022 10 20.
Article em En | MEDLINE | ID: mdl-36264623
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Aminoacil-RNA de Transferência Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Aminoacil-RNA de Transferência Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article