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An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention.
Jørsboe, Emil; Andersen, Mette K; Skotte, Line; Stæger, Frederik F; Færgeman, Nils J; Hanghøj, Kristian; Santander, Cindy G; Senftleber, Ninna K; Diaz, Lars J; Overvad, Maria; Waples, Ryan K; Geller, Frank; Bjerregaard, Peter; Melbye, Mads; Larsen, Christina V L; Feenstra, Bjarke; Jørgensen, Marit E; Grarup, Niels; Moltke, Ida; Albrechtsen, Anders; Hansen, Torben.
Afiliação
  • Jørsboe E; Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Andersen MK; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Skotte L; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Stæger FF; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Færgeman NJ; Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Hanghøj K; Villum Center for Bioanalytical Sciences, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Denmark.
  • Santander CG; Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Senftleber NK; Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Diaz LJ; Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Overvad M; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
  • Waples RK; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
  • Geller F; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
  • Bjerregaard P; Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Melbye M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Larsen CVL; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
  • Feenstra B; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Anders Koch; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Jørgensen ME; K.G.Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology (NTNU), Norway.
  • Grarup N; Center for Fertility and Health, Norwegian Institute of Public Health, Norway.
  • Moltke I; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
  • Albrechtsen A; Greenland Centre for Health Research, University of Greenland, Nuuk, Greenland.
  • Hansen T; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
HGG Adv ; 3(4): 100118, 2022 Oct 13.
Article em En | MEDLINE | ID: mdl-36267056
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article