Recombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses.

Krämer, Nadine; Schütz, Martin; Mato, Uxía Gestal; Herhaus, Lina; Marschall, Manfred; Zimmermann, Christine

Krämer, Nadine; Schütz, Martin; Mato, Uxía Gestal; Herhaus, Lina; Marschall, Manfred; Zimmermann, Christine.

Afiliação

Krämer N; University Medical Center, Institute for Virology, University of Mainz, 55131 Mainz, Germany.
Schütz M; Institute for Clinical and Molecular Virology, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Mato UG; School of Medicine, Institute of Biochemistry II, Goethe University, 60598 Frankfurt, Germany.
Herhaus L; School of Medicine, Institute of Biochemistry II, Goethe University, 60598 Frankfurt, Germany.
Marschall M; Institute for Clinical and Molecular Virology, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Zimmermann C; University Medical Center, Institute for Virology, University of Mainz, 55131 Mainz, Germany.

Viruses ; 14(10)2022 10 17.

Article em En | MEDLINE | ID: mdl-36298840

Assuntos

Citomegalovirus; DNA Viral; Humanos; Citomegalovirus/fisiologia; DNA Viral/metabolismo; Fosfotransferases (Aceptor do Grupo Álcool)/genética; Fosfotransferases (Aceptor do Grupo Álcool)/metabolismo; Replicação Viral; Trifosfato de Adenosina/metabolismo; Fosforilação

Palavras-chave

BACmid-derived recombinant HCMV; analog-sensitive pUL97 variant; functional analyses; human cytomegalovirus (HCMV); pUL97-specific inhibitors; protein kinase pUL97; viral kinase activity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Viral / Citomegalovirus Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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