Bioactive Saponins of Primula vulgaris Huds. Promote Wound Healing through Inhibition of Collagenase and Elastase Enzymes: in Vivo, in Vitro and in Silico Evaluations.

Kahraman, Cigdem; Sari, Suat; Küpeli Akkol, Esra; Tatli Cankaya, Irem

Kahraman, Cigdem; Sari, Suat; Küpeli Akkol, Esra; Tatli Cankaya, Irem.

Afiliação

Kahraman C; Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, 06100, Ankara, Turkey.
Sari S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, 06100, Ankara, Turkey.
Küpeli Akkol E; Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330, Ankara, Turkey.
Tatli Cankaya I; Department of Pharmaceutical Botany, Faculty of Pharmacy, Hacettepe University, 06100, Ankara, Turkey.

Chem Biodivers ; 19(12): e202200582, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36310134

Assuntos

Primula; Saponinas; Elastase Pancreática; Saponinas/farmacologia; Simulação de Acoplamento Molecular; Extratos Vegetais; Cicatrização; Colagenases/metabolismo

Palavras-chave

QM-polarized ligand docking; enzyme inhibitory activity; molecular docking; primulasaponins; wound healing activity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saponinas / Primula Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saponinas / Primula Idioma: En Ano de publicação: 2022 Tipo de documento: Article