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Host Biomarkers Reflect Prognosis in Patients Presenting With Moderate Coronavirus Disease 2019: A Prospective Cohort Study.
Chandna, Arjun; Mahajan, Raman; Gautam, Priyanka; Mwandigha, Lazaro; Kumar, Pragya; Varghese, George M; Koshiaris, Constantinos; Lubell, Yoel; Burza, Sakib.
Afiliação
  • Chandna A; Cambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
  • Mahajan R; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
  • Gautam P; Médecins Sans Frontières, New Delhi, India.
  • Mwandigha L; Department of Infectious Diseases, Christian Medical College, Vellore, India.
  • Varghese GM; Department of Community and Family Medicine, All India Institute of Medical Sciences, Patna, India.
  • Koshiaris C; Department of Infectious Diseases, Christian Medical College, Vellore, India.
  • Lubell Y; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
  • Burza S; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Open Forum Infect Dis ; 9(10): ofac526, 2022 Oct.
Article em En | MEDLINE | ID: mdl-36320192
ABSTRACT
Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-response relationships with subsequent disease progression and could potentially be useful for multiple use-cases.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article