Lactate from the tumor microenvironment - A key obstacle in NK cell-based immunotherapies.

Jedlicka, Marek; Feglarová, Tereza; Janstová, Lucie; Hortová-Kohoutková, Marcela; Fric, Jan

Lactate from the tumor microenvironment - A key obstacle in NK cell-based immunotherapies.

Jedlicka, Marek; Feglarová, Tereza; Janstová, Lucie; Hortová-Kohoutková, Marcela; Fric, Jan.

Afiliação

Jedlicka M; Department of Modern Immunotherapy, Institute of Hematology and Blood Transfusion, Prague, Czechia.
Feglarová T; Faculty of Science, Charles University in Prague, Prague, Czechia.
Janstová L; Department of Modern Immunotherapy, Institute of Hematology and Blood Transfusion, Prague, Czechia.
Hortová-Kohoutková M; Department of Modern Immunotherapy, Institute of Hematology and Blood Transfusion, Prague, Czechia.
Fric J; Faculty of Science, Charles University in Prague, Prague, Czechia.

Front Immunol ; 13: 932055, 2022.

Article em En | MEDLINE | ID: mdl-36330529

Assuntos

Neoplasias; Microambiente Tumoral; Humanos; Ácido Láctico; Imunoterapia; Células Matadoras Naturais; Neoplasias/terapia

Palavras-chave

NK cell; T cell; cytotoxicity; immunometabolism; immunosuppression,; immunotherapy; lactate

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microambiente Tumoral / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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